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Mischelle McMillin
Verified Customer
Love this product! Absorbs in, light and hydrating. I have been using for a few weeks and my skin has never felt better

HA⁵® Hydra Collagen Replenish + Restore Hydrator

HA⁵® Hydra Collagen Replenish + Restore Hydrator

 (25860 Reviews)
Regular price $185.99
Regular price $185.99 Sale price $192.00
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*For all skin type *TSA Friendly

An Evolution in Hydration – Introducing the next-gen HA⁵®, now with 2X more hyaluronic acid. Enhanced with Hydra Collagen for instant hydration and smoothness, plus Advanced VITISENSCE® Technology to replenish natural humectants, including HA and help restore skin's hydration reservoir.

Provides immediate hydration lasting up to 48 hours. Enjoy visibly plump, dewy, and healthier-looking skin with fewer lines.

Silicone-free • Non-comedogenic • Sulfate-free • Made with Vegan Collagen • Lightweight • Fragrance-free • Paraben-free • Pilling-free

Store at room temperature 15°C - 30°C (59°F - 86°F).

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Key Benefits1

  • HA⁵® Hydra Collagen Replenish + Restore Hydrator attracts and retains water for instant hydration and visibly plump, smooth skin
  • In a clinical study, patients reported they looked ~ 3 years younger by week 121
  • Clinically proven to improve hydration and support skin health by addressing the skin barrier and water-holding capacity

Key Ingredients

Advanced VITISENSCE® Technology

  • Avocado Oil Esters - Supports skin's natural hydration and skin's water-holding abilities
  • Vitamin F - Supports skin barrier and prevents water loss
  • Passion Fruit Seed Oil - Enhances skin health and supports skin's water and nutrition flow
  • Vitis Flower Stem Extract and Lotus Sprout Extract - Protect against oxidative stress

Proprietary HA⁵® Hydra Collagen Complex

  • Hydration Collagen - vegan collagen that attracts and retains water for instant hydration and smoothness

5 Forms of HA:

-Nano-hyaluronic acid - Soothes skin

-Noncross-linked HA - For smoothness and hydration

-Liposomally Encapsulated HA - For immediate hydration

-Cross-linked HA - Provides long-lasting hydration

-Vectorized Time Release HA - A SkinMedica® proprietary ingredient for sustained release of HA

    Ingredients

    Aqua/Water/Eau, Glycerin, Caprylic/Capric Triglyceride, Shorea Stenoptera Seed Butter, C9-12 Alkane, Propanediol, Linoleic Acid, Sodium Acrylates Copolymer, Passiflora Edulis Seed Oil, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Nelumbo Nucifera Germ Extract, Vegan Biomimetic Collagen, Butyl Avocadate, Trehalose, Serine, Vitis Vinifera (Grape) Flower Cell Extract, Linolenic Acid, Urea, Caprylhydroxamic Acid, Algin, Polyglutamic Acid, Tocopherol, Oleic Acid, Pullulan, Palmitic Acid, Glyceryl Glucoside, Coco-Caprylate/Caprate, Lecithin, 1,2-Hexanediol, Pentylene Glycol, Stearic Acid, Benzoic Acid, Caprylyl Glycol, Polysorbate 20, Dehydroacetic Acid, Glyceryl Polyacrylate, Potassium Phosphate, Benzyl Alcohol, Disodium Phosphate, Sodium Benzoate.


    • Female, African American, Age 58, Fitzpatrick Skin Type V. Unretouched photos, taken in parallel polarized lighting of subject at baseline and immediately after using HA⁵® Hydra Collagen Replenish + Restore Hydrator.Individual results may vary.

    • Female, African American, Age 58, Fitzpatrick Skin Type V. Unretouched photos, taken in parallel polarized lighting of subject at baseline and immediately after using HA⁵® Hydra Collagen Replenish + Restore Hydrator.Individual results may vary.

    • Female, African American, Age 58, Fitzpatrick Skin Type V. Unretouched photos, taken in parallel polarized lighting of subject at baseline and immediately after using HA⁵® Hydra Collagen Replenish + Restore Hydrator.Individual results may vary.

    • Female, African American, Age 58, Fitzpatrick Skin Type V. Unretouched photos, taken in parallel polarized lighting of subject at baseline and immediately after using HA⁵® Hydra Collagen Replenish + Restore Hydrator.Individual results may vary.

      How to use

      • When to Apply Apply twice daily— morning and at night—after cleansing and treating your skin. Use before you moisturize and apply SPF.
      • Where to Apply Apply to face, neck and chest, or any area needing hydration.
      • How to Apply Dispense 1 to 2 pumps in your palm and smooth onto the skin. Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.

      Behind the Formula:Why it Works

      HA⁵® Hydra Collagen Replenish + Restore Hydrator is our next level hydrator solution clinically proven to visibly improve hydration and support skin health, by improving the skin's barrier and water-holding capacity.

      It has 2X more HA than the previous formulation to provide optimal, immediate hydration. It's our first and only hydrator to use our proprietary HA⁵® Hydra Collagen technology and Advanced VITISENSCE® Technology, targeting existing collagens deeper within the skin to boost hydration naturally. Provides long-term results that reduce the appearance of lines and redness.

      Additional Information

      -What differentiates HA® Hydra Collagen Replenish + Restore Hydrator from the legacy HA® Rejuvenating Hydrator product?Modernizing our legacy HA⁵® formulation takes HA⁵® Hydra Collagen Replenish + Restore Hydrator to the next level of hydrator innovation. NEW Hydra Collagen is a vegan collagen that attracts and retains water for instant hydration and smoothness. ADVANCED VITISENSCE® TECHNOLOGY replenishes the natural HA, biohumectants, and hydration-boosting collagens within the skin to support the skin's hydration reservoir. Now, hydration lasts twice as long (48 hours vs 24 hours) compared to the original formulation.

      -What’s the difference between a moisturizer and a hydrator?A moisturizer is a cosmetic cream or lotion made with humectants or occlusive or a combination of that prevents skin dryness. A hydrator is a cosmetic treatment product that promotes epidermal health by supporting the skin’s natural biomolecules, including HA, other humectants and hydration-boosting collagens.

      -What’s the difference between dehydrated and dry skin?Dry skin is a skin type, while dehydration is a skin condition. In both, the skin undergoes transepidermal water loss, or evaporation of water from inside the body. With this water loss, the enzymes that normally help the skin shed cells cannot function properly, resulting in a buildup of cells that makes the skin look rough and dry, contributing to the appearance of fine lines and wrinkles. Dry skin can be genetic or a symptom of systemic disease. It is caused either by the inadequate production of oil, called sebum, or by an imbalance of fatty acids, ceramide, and cholesterol in the stratum corneum, the barrier layer of the skin. Age is also a factor since we experience a decline in a main hormone that triggers sebum production. Dehydrated skin still produces sebum, but is temporarily dry because of various factors, including environmental effects such as a dry climate, harsh detergents, or skin products. It is also caused by a temporary imbalance of fatty acids and ceramides in the skin’s barrier layer, resulting in a temporary spike in transepidermal water loss.

      -How should HA⁵®  Hydra Collagen Replenish & Restore Hydrator be used within a regimen?HA⁵®  Hydra Collagen Replenish & Restore Hydrator can be used with any SkinMedica® product or regimen to support hydration. It should be applied immediately before moisturizer in a normal regimen.

      In Clinical Studies

      • 93% of patients reported this product made their skin look dewy and healthy at 2 weeks (n=30)
      • 93% reported skin looked visibly plumper at week 12 (n=29)
      • 97% of patients agreed this product improved their skin quality at week 12 (n=29)
      • 100% of patients agreed this product made them feel confident about their skin at week 12 (n=29)

      SkinMedica®, an Allergan Aesthetics Brand.

      There's skincare.Then there's scientific skincare.

      Since 1999, we've been a leader in professional-grade skincare. With over 25 years of innovation, we hold ourselves to the highest standards of scientific rigor - striving toward new findings and delivering products that revolutionize skincare. 

      200+

      global clinical efficacy studies completed

      90+

      peer-reviewed publications

      50+

      US patents granted


       23 SkinMedica®  US patents

      28 DiamondGlow®  US patents

      Our Labs

      Our approach to product innovation relies on research and bridging the gap between biological processes, revolutionary formulations, and clinical results.

      SkinMedica®  has in-house laboratory, which makes working directly with clinical researchers possible - throughout every step of product creation.

      • Biology and Bioactivity

      • Formulations

      • Clinical

        "The most rewarding part of what we can do is watching the changes in a patient's self-esteem and happiness."

        -Dr. Richard Fitzpatrick, Dermatologist & Co-founder of SkinMedica®